tradd (Santa Cruz Biotechnology)
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Santa Cruz Biotechnology
tradd
Tradd, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 112 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+tradd/TRADD+Antibody/pm41421355-295-65-66
Average 93 stars, based on 112 article reviews
Tradd, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 112 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+tradd/TRADD+Antibody/pm41421355-295-65-66
Average 93 stars, based on 112 article reviews
tradd - by Bioz Stars,
2026-10
93/100 stars
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Western Blot:Article Title: Rubiarbonol B induces RIPK1-dependent necroptosis via NOX1-derived ROS production Article Snippet: .. Antibodies and reagents All commercial antibodies and chemicals were purchased from the following resources: anti-caspase-8 (#9746 ), anti-caspase-3 (#9662), anti-Bid (#2002), anti-Bcl-2 (#2872), anti-Bcl-xL (#2762), anti-RIPK3 (#13526, for WB and IP), anti-phospho-RIPK3-S227 (#93654), anti-phospho-MLKL-S358 (#37333), antiphospho-RIPK1-S166 (#65746), anti-phospho-IKKα/β-S176/180 (#2697), anti- IκBα (#9242), and antiphospho-p65-S536 (#3033) antibodies were from Cell Signaling Technology (Beverly, MA, USA); anti-FADD (sc-5559), anti-Mox1 (sc-518023), anti-TRADD (sc-46653), and anti-TNFR1 (sc-8436) antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA, USA); anti-Actin antibody (A2066), anti-Flag antibody (F7425), Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), Cycloheximide (CHX), Dihydroethidium (DHE), MitoTEMPO, Apocynin, Diphenyleneiodonium (DPI), Butylated hydroxyanisole (BHA), Necrostatin-1 (Nec-1), and Necrosulfonamide (NSA) were from Sigma-Aldrich (St. Louis, MO, USA); MitoTracker Green and MitoSox Red were from Invitrogen (Franklin, MA, USA); anti-PARP (556362) and anti-RIPK1 (556395) antibodies were from BD Biosciences (San Diego, CA, USA); anti-MLKL (ab184718) antibody was from Abcam (Cambridge, MA, USA); recombinant TNF-α (410-MT) and anti-caspase-8 (AF-705, for IP), antiTNFR1 (AF-425, for IP) antibodies were from R&D system (Minneapolis, MN, USA); recombinant human TRAIL ligand (310-04) was from PeproTech (Rocky Hill, NJ, USA); SM-164, benzyloxy-carbonyl-Asp-(OMe)Glu-(OMe)-Val-Asp-(OMe)- uoromethyl ketone (z-DEVD-fmk), benzyloxy-carbonyl-Ile-Glu-(OMe)-Tyr-Asp(OMe)- uoromethyl ketone (z-IETD-fmk), arbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]uoromethylketone (z-VAD-fmk), and GSK-872 were from MedChemExpress (Monmouth Junction, NJ, USA). .. Article Title: A novel format of TNF-α binding affibody molecule ameliorate coronary artery endothelial injury in a mouse model of Kawasaki disease. Article Snippet: Kawasaki disease (KD) is a disease characterized by systemic immune vasculitis that often involves coronary arteries and can result in long-term cardiovascular sequelae.. Different strategies for treatment of KD-and KDinduced coronary artery lesions are currently under investigation, including passive immunization with antiTNFα monoclonal antibodies (mAbs).. Herein, we examine the potential therapeutic capabilities of a novel type of TNFα-targeting agent based on an affibody molecule possessing fundamentally different properties than mAbs. Recombinant:Article Title: Rubiarbonol B induces RIPK1-dependent necroptosis via NOX1-derived ROS production Article Snippet: .. Antibodies and reagents All commercial antibodies and chemicals were purchased from the following resources: anti-caspase-8 (#9746 ), anti-caspase-3 (#9662), anti-Bid (#2002), anti-Bcl-2 (#2872), anti-Bcl-xL (#2762), anti-RIPK3 (#13526, for WB and IP), anti-phospho-RIPK3-S227 (#93654), anti-phospho-MLKL-S358 (#37333), antiphospho-RIPK1-S166 (#65746), anti-phospho-IKKα/β-S176/180 (#2697), anti- IκBα (#9242), and antiphospho-p65-S536 (#3033) antibodies were from Cell Signaling Technology (Beverly, MA, USA); anti-FADD (sc-5559), anti-Mox1 (sc-518023), Staining:Article Title: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development Article Snippet: .. Sections were then stained with other:Article Title: Polarity protein AF6 functions as a modulator of necroptosis by regulating ubiquitination of RIPK1 in liver diseases Article Snippet: Antibodies and other reagents were obtained as follows: anti-AF6 and anti-RIPK1(receptor-interacting serine/threonine kinase 1) antibodies from BD Transduction Laboratories; anti-pRIPK1(S166), anti-TNFR1(TNF receptor superfamily member 1A), anti-Hsp90(heat shock protein 90), and anti-GAPDH(glyceraldehyde-3-phosphate dehydrogenase) antibodies from Cell Signaling Technology; anti-pRIPK3(Ser232) (receptor-interacting serine/threonine kinase 3), anti-pMLKL(Ser345)(mixed lineage kinase domain-like pseudokinase), anti-MLKL and anti-CYLD(CYLD lysine 63 deubiquitinase) antibodies from abcam; anti-USP21, anti-FADD (Fas-associated via death domain), anti-TRAF2(TNF receptor-associated factor 2), and anti-TRADD( Article Title: MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death. Article Snippet: TNF is a master proinflammatory cytokine whose pathogenic role in inflammatory disorders can, in certain conditions, be attributed to RIPK1 kinase-dependent cell death.. Survival, however, is the default response of most cells to TNF stimulation, indicating that cell demise is normally actively repressed and that specific checkpoints must be turned off for cell death to proceed.. We identified RIPK1 as a direct substrate of MK2 in the TNFR1 signalling pathway. Immunoprecipitation:Article Title: Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms. Article Snippet: Inflammation has recently emerged as an important contributor for cardiovascular disease development and participates pivotally in the development of neointimal hyperplasia and abdominal aortic aneurysms (AAA) formation.. Kv7.4/KCNQ4, a K channel, is one of the important regulators of vascular function but its role in vascular inflammation is unexplored.. Here, we showed that the expression of Kv7.4 channel was elevated in the neointima and AAA tissues from mice and humans. Incubation:Article Title: Kv7.4 channel is a key regulator of vascular inflammation and remodeling in neointimal hyperplasia and abdominal aortic aneurysms. Article Snippet: Inflammation has recently emerged as an important contributor for cardiovascular disease development and participates pivotally in the development of neointimal hyperplasia and abdominal aortic aneurysms (AAA) formation.. Kv7.4/KCNQ4, a K channel, is one of the important regulators of vascular function but its role in vascular inflammation is unexplored.. Here, we showed that the expression of Kv7.4 channel was elevated in the neointima and AAA tissues from mice and humans. Article Title: Structural and functional elucidation of NF-κB signaling by the p75 neurotrophin receptor through recruitment of TRADD Article Snippet: .. Cells were then incubated overnight at 4 °C with anti-p75 NTR (Promega; G323A; 1:300) and |
